The department of Biochemistry is a comprehensive department involved in patient care, teaching and research. A wide spectrum of clinical chemistry investigations including tumor markers are being routinely carried out in the department for the out-patients and in-patients of our hospital and also patients referred from other centers. The department is well equipped with State of art analyzers (for routine work) and has a regular quality control program to ensure the accuracy of laboratory results reported.
Our laboratory does more than 7,00,000 tests annually. Turn around time for all the investigations is 3 hours. House keeping and waste management is done as per the Institute waste management policy.
The department is actively engaged in several teaching programs. The 3 years B.Sc. Medical Laboratory Technology course is being conducted under the Rajiv Gandhi University of Health Sciences. Undergraduate and postgraduate medical students and students enrolled in the super specialty Oncology courses of the Medical University and from neighboring institutes are regularly posted to the department for training.
In addition, the department extends facilities and guidance to postgraduate medical and dental students for their dissertation work. A number of undergraduate and post graduate non medical students from Bangalore University and other outside universities are regularly posted to the department for summer training programs.
Our laboratory is recognized by the Bhabha Atomic Research Centre for carrying out in vitro radioisotope work. The department is recognized by the Rajiv Gandhi University of Health Sciences, Karnataka State, to carry out research work for doctoral program. Our faculty members are recognized guides and have students registered for Ph.D. in Medical.
|
Department of Biochemistry - Statistics from January 2022 - December 2022 (Routine)
|
|
Type of Investigations
|
Jan
|
Feb
|
Mar
|
Apr
|
May
|
Jun
|
Jul
|
Aug
|
Sept
|
Oct
|
Nov
|
Dec
|
Control
|
Total
|
|
AFP
|
88
|
95
|
113
|
108
|
87
|
108
|
96
|
98
|
84
|
85
|
92
|
118
|
250
|
1422
|
|
CEA
|
180
|
181
|
241
|
200
|
177
|
219
|
211
|
188
|
196
|
172
|
197
|
215
|
350
|
2727
|
|
CA125
|
177
|
165
|
221
|
181
|
175
|
203
|
168
|
180
|
182
|
156
|
173
|
201
|
350
|
2532
|
|
PSA
|
51
|
41
|
57
|
46
|
50
|
55
|
53
|
47
|
52
|
30
|
44
|
57
|
170
|
753
|
|
Ca19.9
|
88
|
83
|
116
|
101
|
109
|
120
|
121
|
109
|
114
|
89
|
117
|
101
|
170
|
1438
|
|
T3
|
223
|
222
|
272
|
275
|
271
|
314
|
276
|
220
|
206
|
206
|
217
|
203
|
350
|
3255
|
|
T4
|
223
|
222
|
272
|
275
|
271
|
314
|
276
|
221
|
206
|
206
|
217
|
203
|
350
|
3256
|
|
TSH
|
291
|
285
|
363
|
328
|
318
|
370
|
341
|
264
|
244
|
268
|
270
|
285
|
350
|
3977
|
|
TG
|
90
|
106
|
272
|
87
|
56
|
83
|
84
|
61
|
53
|
51
|
61
|
90
|
170
|
1264
|
|
ATG
|
76
|
87
|
76
|
60
|
33
|
64
|
67
|
43
|
41
|
30
|
35
|
70
|
100
|
782
|
|
ATPO
|
3
|
0
|
5
|
2
|
3
|
3
|
2
|
3
|
2
|
0
|
1
|
3
|
60
|
87
|
|
BHCG
|
60
|
67
|
69
|
66
|
53
|
63
|
61
|
55
|
57
|
56
|
57
|
60
|
150
|
874
|
|
Total
|
1550
|
1554
|
2077
|
1729
|
1603
|
1916
|
1756
|
1489
|
1437
|
1349
|
1481
|
1606
|
2820
|
22367
|
STAFF DETAILS
|
Sl.No.
|
Doctors Name
|
Designation
|
|
1
|
Dr. G Ramesh
|
Professor and HOD
|
|
2
|
Dr. K Thriveni
|
Associate Professor
|
|
3
|
Dr. Sandeep Kumar
|
Associate Professor
|
|
4
|
Dr. Akshatha L N
|
Associate Professor
|
|
5
|
Dr. Basavaraj
|
Specialist
|
|
6
|
Sri. S P Vajrakumar
|
Assistant Research Scientist
|
|
7
|
Dr. Rachana
|
Assistant Research Scientist
|
|
8
|
Sri.Narasimhulu D
|
Chief Lab Technician
|
|
9
|
Sri. Shiva Murthy
|
Chief Lab Technician
|
|
10
|
Smt. G S Shivarathnamma
|
Sr. Medical Lab Technician
|
|
11
|
Sri. K B Lingaraju
|
Sr. Medical Lab Technician
|
|
12
|
Smt. S K Kavitha
|
Jr. Medical Lab Technologist
|
|
13
|
Smt. Shashikala
|
Jr. Medical Lab Technologist
|
|
14
|
Smt. Keerthi Mary
|
Jr. Medical Lab Technologist
|
Research activities/projects/completed projects, ongoing and new projects
Completed
- Investigating galectin based potentiation of malignant ovarian cells within an ascites microenvironment.
- “Role of the Cytoplasmic E-Cadherin Fragment in Ovarian Carcinoma and development of plasma based methylation biomarker panel for early diagnosis and prognosis.” (RGUHS).
- “Role of DNA methylation in predicting response to chemotherapy & understanding signalling pathways involved in ovarian carcinoma.” (RGUHS).
- “Aberrant promoter hypermethylation of tumor suppressor genes in endometrial carcinoma- correlation with clinicopathological parameters (RGUHS).
RESEARCH PUBLICATIONS
- Anisha Raju, Karuvaje Thriveni, Shankaranand S Bharatnur, and Ravi Arjunan. Association of (hTERT) Gene Expression with Clinicopathological Parameters in Breast Carcinoma Journal of Cancer Biology & Research.
- Akshtha LN, Dr. Sandeep Kumar, Dr. Ramesh G, Dr. Rachana, Dr. Ramachandra C. Lactate dehydrogenase as an indicator of liver tumors. European journal of Molecular and Clinical Medicine. 9(1) 2022. 826-830.
- Akshatha LN, Dr. Sandeep Kumar, Dr. Ramesh G, Dr Lokesh V To assess the serum lipid levels in cancer patients at the initiation of chemotherapy in relation to the most relevant prognostic factors Journal of Pharmaceutical Negative Results. (13), Special Issue 9, 2022.
RESEARCH PUBLICATIONS (Archive)
1. Kumar S, Swamy SN, Premalatha CS, Pallavi VR, Gawari R. Aberrant promoter Hypermethylation of RASSF1a and BRCA1 in circulating cell-free tumor DNA serves as a biomarker of ovarian carcinoma. Asian Pacific journal of cancer prevention: APJCP. 2019;20(10):3001.
2. Swamy SN, Kumar S, Devaraj VR, Gawari R. Generation and Characterization of A Carboplatin Resistant Ovarian Cancer Model. Journal of Cancer Science and Clinical Therapeutics.2020;4(3):.
3. Gera S, Kumar S, S, Swamy SN, Bhagat R, Vadaparty A, Gawari R, Bhat R, Dighe RR. Follicle-stimulating hormone is an autocrine regulator of the ovarian cancer metastatic niche through notch signaling. Journal of the Endocrine Society. 2019 Feb;3(2):340-57.
4. Kumar S, Swamy SN, Premalatha CS, Pallavi VR, Gawari R. Down Regulation of RASSF1a, APC and GSTP1 is Associated with Epithelial Ovarian Carcinoma Tumorigenesis. Archives of Clinical and Biomedical Research. 2020;4(4):349-60.
5. L.Krishnamoorthy, G.Ramaswamy, R.Gomathy, V.Kannan, Ramesh G and N.Anantha.“The role of free radical detoxifying systems in the cellular response to radiation therapy in carcinoma of the uterine cervix”. In recent Aspects of cellular and applied radiobiology. Ed.F.H.Schneweis and R.N.Sharma, vol 30, 162 -164,1998.
6. Sunil Chandy, Sadananda Adiga M N, Ramesh G, Girija Ramaswamy, Vijayakumar M, Savithri H S and Lakshmi Krishnamoorthy. “Methylenetetrahydrofolate reductase 677 C®T and 1298 A®C gene polymorphisms and its relation to levels of homocysteine, folate, Vitamin B12 and Vitamin B2 in colorectal cancer”. Austral-Asial J Cancer, 9(2), 91-100, April 2010.
7. Rani James,G. Ramesh, Lakshmi Krishnamoorthy, Triveni K, Vijaylaxmi Deshmane, P P Bapsy, Girija Ramaswamy. “Plasma VEGF as a marker of therapy in breast cancer patients”. Austral Asian J of Cancer 2011; 10(3); 189-95.
8. Rahul Bhagat, Shilpa Chadaga, C.S. Premlatha, G.Ramesh, C. Ramesh, V.R. Pallavi, Lakshmi Krishnamoorthy. “Aberrant promoter methylation of RASSF1A and APC genes in epithelial ovarian carcinoma development”. Cell Oncol (2012) 35: 473-479.
9. Rahul Bhagat, C. S. Premalata, V. Shilpa, V. R. Pallavi, G. Ramesh, C. R. Vijay & Lakshmi Krishnamoorthy “Altered expression of β-catenin, Ecadherin, and E-cadherin promoter methylation in epithelial ovarian carcinoma”. Tumor Biol. DOI 10.1007/s13277-013-0797-9. April -2013.
10. Rahul Bhagat, Sandeep K, V. Shilpa , C. S. Premalata, , V. R. Pallavi, G. Rameshand Lashmi K. “Epigenetic alterations of p16 and Retinoic Acid receptor beta genes in the development of epithelial ovarian carcinoma” Tumor Biology. DOI 10.10007/s13277-014-213-1 (2014).
11. Shilpa V, Rahul B, C S Premalatha, Pallavi V R, G.Rameshand Lakshmi K “BRCA1 promoter hypermethylation and protein expression in ovarian carcinoma- An Indian Study. Tumor Biology 2014; 35:4277-424. DOI:10.1007/s13277-013-1558-5.
12. Bhaskari Janardhan; Shilpa V; Rahul B; Premalatha C.S.; Pallavi V.R.; Ramesh G; Lakshmi Krishnamoorthy, 'Investigating impact of Vascular Endothelial Growth Factor polymorphisms in epithelial ovarian cancers: A study in the Indian population', Accepted for Publication in Plos One.
13. Thriveni K,Raju A, Kumar RV, Krishnamurthy S, Chaluvarayaswamy R. Patterns of Relative Telomere Length in Associated with hTERT Gene Expressionin the Tissue of Breast Cancer Patients Clin Breast Cancer.2019;19:27-34.
14. Thriveni K,Raju A, Ramaswamy G, Krishnamurthy S, Kumar RV. Tumor necrosis factor: An inflammatory microenvironment marker in primary breast cancer patients. Int J Mol Immuno Oncol 2018;3:24-27.
15. Thriveni K,Raju A, Ramaswamy G, Krishnamurthy S, Kumar RV. An Analysis of Polymorphism Lymphotoxin alpha +252 A>G in South Indian Breast Cancer Patients. International Journal of Hematology and Oncology 2017;27: 229-236.
16. Thriveni K, Raju A. Integrity of genomic DNA isolated from heparin treated human leukocytes by a modified protocol. IOSR Journal of Dental and Medical Sciences 2016; 15:97-100.
17.James R, Ramesh G, Krishnamoorthy L, Thriveni K, Deshmane V, Bapsy PP, Ramaswamy G.Plasma VEGF as a Marker of Therapy in Breast Cancer Patients. Austral-Asian Journal of Cancer 2011;10:189-95.
18. Thriveni K, James R, Krishnamoorthy L, Deshmane V, Bapsy PP, Ramaswamy G. Upregulation of telomerase activity by HER-2/neu and its significance in breast cancer. International Journal of Haematology and Oncology.2010;3:141-147.
19. Thriveni K, James R, Krishnamoorthy L, Deshmane V, Bapsy PP, Ramaswamy G. Serum transaminases ratio in breast cancer patients. Austral Asian Journal of Cancer.2009;8:199-20.
20. Girija Ramaswamy, Vasanthi Rao, Lakshmi Krishnamoorthy, Ramesh, Gomathy R and Renuka Devi D. “Serum level of bone alkaline phosphatase in breast and prostate cancers with bone metastasis”. Ind. J. Clin Biochemistry. 15(2), 110-113, (2000)
21. Rani James, Ramesh, Lakshmi Krishnamoorthy, Rahul Bhagat, Shilpa Chadaga, Vijayalaxmi Deshmane, Girija Ramaswamy. “Prevalence of +405G>C,−1154G>A Vascular Endothelial Growth Factor Polymorphism in Breast Cancer”. Ind J Clin Biochem. 2013. DOI 10.1007/s12291-013-0307-2, Feb-2013.
22. Shilpa V, Rahul B, C S Premalatha, Pallavi V R, Rameshand Lakshmi K. “The relationship between romoter methylation and tissue expression of MGMT gene in ovarian cancer. Indian Journal of Medical Research(2014).
23. Ramesh, Shalini N. Swamy, S. Sandeep Kumar, C. S. Premalata, V. R. Pallavi. ”Aberrant Promoter Hypermethylation of Death Associated Protein Kinase (DAPK) in Epithelial Ovarian Carcinoma”. Journal of Evidence based Medicine and Healthcare, 2015.
24. Ramesh, S. Sandeep Kumar, Shalini N. Swamy, C. S. Premalata, V. R. Pallavi. ”A Study on the Aberrant Promoter Hypermethylation of RAR-β Gene in the Plasma of Epithelial Ovarian Carcinoma Patients”. Journal of Evidence based Medicine and Healthcare, 2015.
25. Ramesh, S. Sandeep Kumar, Shalini N. Swamy, C. S. Premalata, V. R. Pallavi. ”The Aberrant Promoter Hypermethylation Pattern of the Anti-Angiogenic TSP1 Gene in Epithelial Ovarian Carcinoma: An Indian Study”. Journal of Evidence based Medicine and Healthcare, 2015.
26. Rani James, Rahul Bhagat, Shilpa Chadaga, Thriveni K, Lakshmi Krishnamoorthy, G Ramesh,Girija Ramaswamy. “Association of vascular endothelial growth factor (VEGF) single nucleotide polymorphisms(SNPs) and prognosis of Breast cancer patients. Accepted for Publication in Indian Journal of Cancer.
27. Sandeep Kumar, Noopur Nelson Manisha Roy Govardhan Khaleel Pallavi Ramesh. IS LOCALLY ADVANCED CANCER CERVIX ASSOCIATED WITH HYPOALBUMINEMIAAND INCREASED GRANULOCYTE AND LYMPHOCYTE RATIO? Volume-8 | Issue-3 | March-2019 | PRINT ISSN No 2277 – 8179.
28. Kumar S, Roy M, Nelson N, Govardhan G, Khaleel K, R. P, Ramesh. Pre-treatment de-ritis ratio as a marker for cervical cancer: a study at regional cancer centre. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2020Nov.27];7(3):162-9.
29. Kumar S, Swamy SN, Premalatha CS, Pallavi VR, Gawari R. Aberrant promoter Hypermethylation of RASSF1a and BRCA1 in circulating cell-free tumor DNA serves as a biomarker of ovarian carcinoma. Asian Pacific journal of cancer prevention: APJCP. 2019;20(10):3001.
30. Gera S, Kumar S, S, Swamy SN, Bhagat R, Vadaparty A, Gawari R, Bhat R, Dighe RR. Follicle-stimulating hormone is an autocrine regulator of the ovarian cancer metastatic niche through notch signaling. Journal of the Endocrine Society. 2019 Feb;3(2):340-57.
31. Sandeep Kumar, Noopur Nelson Manisha Roy Govardhan Khaleel Pallavi Ramesh. Is Locally Advanced Cancer Cervix Associated With Hypoalbuminemiaand Increased Granulocyte And Lymphocyte Ratio? Volume-8 | Issue-3 | March-2019 | PRINT ISSN No 2277 – 8179.
32. Kumar S, Roy M, Nelson N, Govardhan G, Khaleel K, R. P, G. Ramesh. Pre-treatment de-ritis ratio as a marker for cervical cancer: a study at regional cancer centre. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2020Nov.27];7(3):162-9.
33. Thriveni K,Raju A, Kumar RV, Krishnamurthy S, Chaluvarayaswamy R. Patterns of Relative Telomere Length in Associated with hTERT Gene Expressionin the Tissue of Breast Cancer Patients Clin Breast Cancer.2019;19:27-34.
34. Thriveni K,Raju A, Ramaswamy G, Krishnamurthy S, Kumar RV. Tumor necrosis factor: An inflammatory microenvironment marker in primary breast cancer patients. Int J Mol Immuno Oncol 2018;3:24-27.
35. Thriveni K,Raju A, Ramaswamy G, Krishnamurthy S, Impact of Gene Polymorphism of TNFα rs 1800629 and TNFβ rs 909253 on Plasma Levels of South-Indian Breast Cancer Patients. Ind J Cancer.2018;55:179-183.
36. Sandeep Kumar, Noopur Nelson Manisha Roy Govardhan Khaleel Pallavi Ramesh. Is Locally Advanced Cancer Cervix Associated With Hypoalbuminemiaand Increased Granulocyte And Lymphocyte Ratio? Volume-8 | Issue-3 | March-2019 | PRINT ISSN No 2277 – 8179.
37. Kumar S, Roy M, Nelson N, Govardhan G, Khaleel K, R. P, G. Ramesh. Pre-treatment de-ritis ratio as a marker for cervical cancer: a study at regional cancer centre. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2020Nov.27];7(3):162-9.
38. Thriveni K,Raju A, Ramaswamy G, Krishnamurthy S, Impact of Gene Polymorphism of TNFα rs 1800629 and TNFβ rs 909253 on Plasma Levels of South-Indian Breast Cancer Patients. Ind J Cancer.2018;55:179-183.
39. Thriveni K, Deshmane V, Ramaswamy G, Krishnamoorthy L. Diagnostic Significance of CA15-3 with combination of HER-2/neu values at 85th percentiles in breast cancer. Ind J Clin Biochem. 2013; 28:136–140.
40. James R, Thriveni K,Krishnamoorthy L , Deshmane V , Bapsy PP, Ramaswamy G. Clinical outcome of adjuvant endocrine treatment according to Her-2/neu status in breast cancer. Indian J Med Res. 2011; 133: 70-75.
41. James R, Thriveni K, Bapsy PP, Krishnamoorthy L, Mukherjee G , Deshmane V , Ramaswamy G. Evaluation of immunohistochemistry (IHC) and enzyme linked immunosorbent assay (ELISA) for HER-2/neu expression in breast carcinoma. Ind.J.Clin Biochemistry 2008; 23: 345-351.
42. Thriveni Kand Girija Ramaswamy. “A study of serum Her-2/neu expression in cancer breast along with other prognostic factors like CEA, CA15-3 and tissue telomerase activity”. D. Thesis, Rajiv Gandhi University of Health Sciences, Karnataka. 2008.
43. Thriveni K, Krishnamoorthy L, Ramaswamy G. Correlation study of carcino embryonic antigen and cancer antigen 15.3 in breast cancer patients. Ind.J.Clin Biochemistry 2007; 22: 57-60.
44. Thriveni K, Krishnamoorthy L, Ramaswamy G. Clinical utility of serum human epidermal receptor-2/neu in breast cancer patients. Indian J Med Res 2007; 125: 137-142.
45. Sandeep Kumar, Noopur Nelson Manisha Roy Govardhan Khaleel Pallavi Ramesh. Is Locally Advanced Cancer Cervix Associated With Hypoalbuminemiaand Increased Granulocyte And Lymphocyte Ratio? Volume-8 | Issue-3 | March-2019 | PRINT ISSN No 2277 – 8179.
46. Kumar S, Roy M, Nelson N, Govardhan G, Khaleel K, R. P, G. Ramesh. Pre-treatment de-ritis ratio as a marker for cervical cancer: a study at regional cancer centre. Int J Med Res Rev [Internet]. 2019Jun.30 [cited 2020Nov.27];7(3):162-9.
47. Kharb, S. Kumarand Z.S. Kundu, 2013. Implications of Raised Folate and Lowered Vitamin B12in Osteosarcoma. American Journal of Biochemistry and Molecular Biology, 3: 182-187.
48. Kharb S, Kumar S, Kundu Z S. Homocysteine, a biomarker of osteosarcoma. J Can Res Ther 2015;11:51-3
49. Shwetha Nagaraj, Akshatha Lalesh Naik, Pratibha K ,Vinay Kumar K. Prostate Specific Antigen in Women with PCOS and Its Correlation with Total Testosterone.International Journal of Biotechnology and Biochemistry ISSN 0973-2691 Volume 15, Number 2 (2019) pp. 87-95.
50. Akshatha LN, Srikrishna R, Kumar S V, Shenoy M T, Mansrekar P A, Hepatic and renal dysfunctions in a malaria endemic region: falciparum malaria vs vivax malaria. Int J Clin Biochem Res 2017;4(4):324-328.
51. L N Akahatha,Shenoy MT, Yadav C, M S R, Kamath N. Bronze diabetes. J Clin Diagn Res. 2015 Apr;9(4):BD01-2. doi: 10.7860/JCDR/2015/11515.5799. Epub 2015 Apr 1. PMID: 26023548; PMCID: PMC4437060.
52. Shenoy MT, D'Souza B, Akshatha LN, D'Souza V, Rajan MG. Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report. Indian J Clin Biochem. 2015 Jul;30(3):360-2. doi: 10.1007/s12291-014-0472-y. Epub 2015 Feb 14. PMID: 26089626; PMCID: PMC4469048.
53. L N Akshatha, M S R, Shenoy MT, P SR, B P. Lead poisoning mimicking acute porphyria! J Clin Diagn Res. 2014 Dec;8(12):CD01-2. doi: 10.7860/JCDR/2014/10597.5315. Epub 2014 Dec 5. PMID: 25653942; PMCID: PMC4316248.
54. Srikrishna R , Akshatha L.N., Dr. Virupaksha L, Vinay Kumar K. Study of HS-CRP, Insulin Resistance and Dyslipidemia as Predictive Markers in PreHpertension”. International Journal of Biotechnology and Biochemistry ISSN 0973-2691 Volume 13, Number 4 (2017) pp. 413-421.
55. Naik AL, Rajan MG, Manjrekar PA, et al. Effect of DOTS Treatment on Vitamin D Levels in Pulmonary Tuberculosis. Journal of Clinical and Diagnostic Research : JCDR. 2017 Apr;11(4):BC18-BC22. DOI: 10.7860/jcdr/2017/24501.9759.
56. Shenoy MT, D'Souza B, Akshatha LN, D'Souza V, Rajan MG. Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report. Indian Journal of Clinical Biochemistry : IJCB. 2015 Jul;30(3):360-362. DOI: 10.1007/s12291-014-0472-y.
57. Akshatha, L.N. & Shenoy, Mamatha & D'Souza, Benedicta & D'Souza, V. & Prabhu, A.K. & Hegde, Anupama & Suresh, Pooja. (2014). Elevated ferritin level in a patient with autoimmune haemolytic anaemia. Biomedicine (India). 34. 412-414.
58. Kuthethur, S., Kumarchandra, R., LN Akshatha.,Gopal, M., Salins, J., & Poojari, P. (2014). Evaluation of serum uric acid /inorganic phosphate ratio in prostate disorders and healthy controls. International Journal of Biomedical and Advance Research, 5(7), 345–347. https://doi.org/10.7439/ijbar.v5i7.807
59. Kumarchandra, Reshma & Akshatha, L.N.(2014). Serum uric acid - Phosphate ratio as a differential diagnostic marker of prostate disorders. International Journal of Pharma and Bio Sciences. 5. B196-B200.
60. Shenoy, Mamatha & D'Souza, Benedicta & Akshatha, L.N.& Puneeth, A. & M S, Rukmini & Hegde, Anupama & D'Souza, V.. (2014). Elevated d-dimer level in acute myeloid leukemia. Biomedicine (India). 34. 267-268.
61. Ramarajan Madan, Naik Akshatha, Hegde Anupama , A Puneeth , Shenoy Mamatha, P Shaheena, Manjrekar Poornima. (2016). Effects of iron status on pulmonary tuberculosis in response to directly observed treatment short course (DOTS). Biomedicine. 36. 015-021.
62. VK Kumar, Shubha , Akshatha LN, Suhas HG ,Sathyajith Thopachiche. Comparison of One-step technique and Two-step technique for Making Impressions using Polyvinylsiloxane for FPD. Journal of Advanced Medical and Dental Sciences Research. |Vol. 6|Issue 4| April 2018. ):55-58.
63. Kuruvanthe S. Rachana,Mallahalli S. Manu, Gopal M. Advirao. Insulin-induced up regulation of lipoprotein lipase in Schwann cells during diabetic peripheral neuropathy. Diabetes and Metabolic syndrome: Clinical Research and Reviews, 2018; DOI:10.1016/j.dsx.2018.03.017.
64. Kuruvanthe S. Rachana, Mallahalli S. Manu, Gopal M. Advirao. Role of insulin in the expression of PMP22, a myelin protein during diabetic peripheral neuropathy. IOSR Journal of Biotechnology and Biochemistry, 2017; 3(6), 50-55.
65. Kuruvanthe S. Rachana, Mallahalli S. Manuand Gopal M. Advirao. Insulin influenced expression of myelin proteins in diabetic peripheral neuropathy. Neuroscience Letters, 2016; 629:110-115.
66. Mallahalli S. Manu, Kuruvanthe S. Rachana, and Gopal M. Advirao. Altered expression of IRS2 and GRB2 in demyelination of peripheral neurons: Implications in diabetic neuropathy. Neuropeptides, 2017; 62:71-19.
67. Mallahalli S. Manu, Kuruvanthe S. Rachana, and Gopal M. Advirao. Insulin inhibits the JNK mediated cell death via up regulation of AKT expression in Schwann cells grown in hyperglycemia. Frontiers in Biology, 2018; DOI:10.1007/s11515-018-1492-4.#
68. Mallahalli S. Manu, Kuruvanthe S. Rachana, and Gopal M. Advirao. Insulin elevates the down regulated OCT-6 transcription factor in diabetic peripheral neuropathy. Genes and Diseases, 2017; DOI:10.1016/j.gendis.2017.12.007.
Awards Obtained
69. Award for Research Publications for the year 2018-19 by Vision Group on Science and Technology Govt, of Karnataka
Official Website of GoK
